Plasmacyte-reticulum cell satellitism in multiple myeloma associated with amyloidosis.

A Rare Presentation of Multiple Myeloma: A Case Report of Hepatic Amyloidosis

The clinically reported case of liver involvement with multiple myeloma (MM) is rare. Amyloidosis, defined as a tissue deposition of clonal light-chain fibrils, has been reported in 10-15% of the MM patients. We described a rare MM patient with the primal presentation of fulminant hepatic failure and biliary system involvement due to amyloidosis. Our patient had the primal symptoms of hyperbili...

Multiple Myeloma with HBs Antigenemia Presented with Hoarseness and Systemic Amyloidosis

I. Requirement of a Plasmacyte-stimulating Factor for the Proliferation of Myeloma Cells in Tissue Culture*

The establishment of cell lines from mouse and human myelomas has been at tempted by a number of laboratories (1-6). Cultures of mouse myelomas have been successfully established with the use of feeder cells (2, 3) and with the use of a phagocytic cell factor (1). Feeder cells and proliferation factors were found to be essential components for the proliferation of antibody-forming cells. Furthe...

Multiple myeloma-amyloidosis presenting as pseudomyopathy.

Amyloidosis is a generic term that refers to the deposition of amyloid fibrils in bodily tissues. Its onset is usually after 40 years of age, with localized or systemic involvement associated with multiple myeloma or chronic inflammatory diseases, and can mimic various rheumatic syndromes. We report the case of a patient with amyloidosis associated with multiple myeloma, showing clinical charac...

LONG-TERM ESTABLISHMENT OF A HUMAN PLASMACYTE CELL LINE DERIVED FROM A PATIENT WITH IgD MULTIPLE MYELOMA

Cell line LA-49, derived from pleural fluid cells of a patient with IgD multiple myeloma, was established in culture and maintained for more than 1 yr. The D-myeloma protein produced in culture was similar to the serum D-myeloma protein in electrophoretic mobility and in delta- and lambda-chain antigens. The plasma cell tumor culture, LA-49, differed from numerous immunoglobulin-producing B-lym...